Systemic Anti-Cancer Therapy (SACT) data standard FHIR IG
0.5.0 - ci-build New Zealand flag

Systemic Anti-Cancer Therapy (SACT) data standard FHIR IG - Local Development build (v0.5.0) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

: Dose adjustment reason - TTL Representation

Draft as of 2026-11-01

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://hl7.org/fhir/ValueSet/an-dose-adjustment-reason> a fhir:ValueSet ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:Resource.id [ fhir:value "an-dose-adjustment-reason"] ;
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ] ;
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: ValueSet an-dose-adjustment-reason</b></p><a name=\"an-dose-adjustment-reason\"> </a><a name=\"hcan-dose-adjustment-reason\"> </a><ul><li>Include these codes as defined in <code>http://snomed.info/sct/21000210109</code><span title=\"Version is not explicitly stated. No matching Code System found\"> version Not Stated (use latest from terminology server)</span><table class=\"none\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td></tr><tr><td>271737000</td><td>Anaemia</td></tr><tr><td>262121000210102</td><td>CNS toxicity</td></tr><tr><td>14760008</td><td>Constipation</td></tr><tr><td>414029004</td><td>Immune system disorder</td></tr><tr><td>262111000210107</td><td>Adjusted body weight calculation</td></tr><tr><td>262101000210105</td><td>Dose rounding</td></tr><tr><td>424122007</td><td>ECOG performance status finding</td></tr><tr><td>105593004</td><td>Electrolyte imbalance</td></tr><tr><td>106176003</td><td>Endocrine finding</td></tr><tr><td>248279007</td><td>Frailty</td></tr><tr><td>106028002</td><td>Musculoskeletal finding</td></tr><tr><td>165517008</td><td>Neutropenia</td></tr><tr><td>49808004</td><td>Advanced age</td></tr><tr><td>74964007</td><td>Other</td></tr><tr><td>407566003</td><td>Patient on maximum tolerated dose</td></tr><tr><td>302226006</td><td>Peripheral neuropathy</td></tr><tr><td>302215000</td><td>Thrombocytopenia</td></tr><tr><td>365921005</td><td>Weight change finding</td></tr></table></li></ul></div>"
  ] ;
  fhir:ValueSet.url [ fhir:value "https://nzhts.digital.health.nz/fhir/ValueSet/canshare-sact-dose-adjustment-reason"] ;
  fhir:ValueSet.version [ fhir:value "0.5.0"] ;
  fhir:ValueSet.name [ fhir:value "DoseAdjustmentReason"] ;
  fhir:ValueSet.title [ fhir:value "Dose adjustment reason"] ;
  fhir:ValueSet.status [ fhir:value "draft"] ;
  fhir:ValueSet.experimental [ fhir:value "false"^^xsd:boolean] ;
  fhir:ValueSet.date [ fhir:value "2026-11-01T21:17:35+00:00"^^xsd:dateTime] ;
  fhir:ValueSet.publisher [ fhir:value "Te aho o te kahu - Cancer Control Agency"] ;
  fhir:ValueSet.contact [
     fhir:index 0 ;
     fhir:ContactDetail.name [ fhir:value "Te aho o te kahu - Cancer Control Agency" ] ;
     fhir:ContactDetail.telecom [
       fhir:index 0 ;
       fhir:ContactPoint.system [ fhir:value "email" ] ;
       fhir:ContactPoint.value [ fhir:value "mailto:david.hay25@gmail.com" ]
     ]
  ] ;
  fhir:ValueSet.description [ fhir:value "Reasons for adjusting the dose of a systemic anti-cancer therapy (SACT) treatment cycle plus other value."] ;
  fhir:ValueSet.jurisdiction [
     fhir:index 0 ;
     fhir:CodeableConcept.coding [
       fhir:index 0 ;
       fhir:Coding.system [ fhir:value "urn:iso:std:iso:3166" ] ;
       fhir:Coding.code [ fhir:value "NZ" ] ;
       fhir:Coding.display [ fhir:value "New Zealand" ]
     ]
  ] ;
  fhir:ValueSet.compose [
     fhir:ValueSet.compose.include [
       fhir:index 0 ;
       fhir:ValueSet.compose.include.system [ fhir:value "http://snomed.info/sct/21000210109" ] ;
       fhir:ValueSet.compose.include.concept [
         fhir:index 0 ;
         fhir:ValueSet.compose.include.concept.code [ fhir:value "271737000" ] ;
         fhir:ValueSet.compose.include.concept.display [ fhir:value "Anaemia" ]
       ], [
         fhir:index 1 ;
         fhir:ValueSet.compose.include.concept.code [ fhir:value "262121000210102" ] ;
         fhir:ValueSet.compose.include.concept.display [ fhir:value "CNS toxicity" ]
       ], [
         fhir:index 2 ;
         fhir:ValueSet.compose.include.concept.code [ fhir:value "14760008" ] ;
         fhir:ValueSet.compose.include.concept.display [ fhir:value "Constipation" ]
       ], [
         fhir:index 3 ;
         fhir:ValueSet.compose.include.concept.code [ fhir:value "414029004" ] ;
         fhir:ValueSet.compose.include.concept.display [ fhir:value "Immune system disorder" ]
       ], [
         fhir:index 4 ;
         fhir:ValueSet.compose.include.concept.code [ fhir:value "262111000210107" ] ;
         fhir:ValueSet.compose.include.concept.display [ fhir:value "Adjusted body weight calculation" ]
       ], [
         fhir:index 5 ;
         fhir:ValueSet.compose.include.concept.code [ fhir:value "262101000210105" ] ;
         fhir:ValueSet.compose.include.concept.display [ fhir:value "Dose rounding" ]
       ], [
         fhir:index 6 ;
         fhir:ValueSet.compose.include.concept.code [ fhir:value "424122007" ] ;
         fhir:ValueSet.compose.include.concept.display [ fhir:value "ECOG performance status finding" ]
       ], [
         fhir:index 7 ;
         fhir:ValueSet.compose.include.concept.code [ fhir:value "105593004" ] ;
         fhir:ValueSet.compose.include.concept.display [ fhir:value "Electrolyte imbalance" ]
       ], [
         fhir:index 8 ;
         fhir:ValueSet.compose.include.concept.code [ fhir:value "106176003" ] ;
         fhir:ValueSet.compose.include.concept.display [ fhir:value "Endocrine finding" ]
       ], [
         fhir:index 9 ;
         fhir:ValueSet.compose.include.concept.code [ fhir:value "248279007" ] ;
         fhir:ValueSet.compose.include.concept.display [ fhir:value "Frailty" ]
       ], [
         fhir:index 10 ;
         fhir:ValueSet.compose.include.concept.code [ fhir:value "106028002" ] ;
         fhir:ValueSet.compose.include.concept.display [ fhir:value "Musculoskeletal finding" ]
       ], [
         fhir:index 11 ;
         fhir:ValueSet.compose.include.concept.code [ fhir:value "165517008" ] ;
         fhir:ValueSet.compose.include.concept.display [ fhir:value "Neutropenia" ]
       ], [
         fhir:index 12 ;
         fhir:ValueSet.compose.include.concept.code [ fhir:value "49808004" ] ;
         fhir:ValueSet.compose.include.concept.display [ fhir:value "Advanced age" ]
       ], [
         fhir:index 13 ;
         fhir:ValueSet.compose.include.concept.code [ fhir:value "74964007" ] ;
         fhir:ValueSet.compose.include.concept.display [ fhir:value "Other" ]
       ], [
         fhir:index 14 ;
         fhir:ValueSet.compose.include.concept.code [ fhir:value "407566003" ] ;
         fhir:ValueSet.compose.include.concept.display [ fhir:value "Patient on maximum tolerated dose" ]
       ], [
         fhir:index 15 ;
         fhir:ValueSet.compose.include.concept.code [ fhir:value "302226006" ] ;
         fhir:ValueSet.compose.include.concept.display [ fhir:value "Peripheral neuropathy" ]
       ], [
         fhir:index 16 ;
         fhir:ValueSet.compose.include.concept.code [ fhir:value "302215000" ] ;
         fhir:ValueSet.compose.include.concept.display [ fhir:value "Thrombocytopenia" ]
       ], [
         fhir:index 17 ;
         fhir:ValueSet.compose.include.concept.code [ fhir:value "365921005" ] ;
         fhir:ValueSet.compose.include.concept.display [ fhir:value "Weight change finding" ]
       ]
     ]
  ] .

# - ontology header ------------------------------------------------------------

<http://hl7.org/fhir/ValueSet/an-dose-adjustment-reason.ttl> a owl:Ontology ;
  owl:imports fhir:fhir.ttl ;
  owl:versionIRI <http://build.fhir.org/ValueSet/an-dose-adjustment-reason.ttl> .